Responsible Embryo Transfer Guidelines

Standard Guidelines for the Transfer of Fresh Embryos

RMIA bases its embryo transfer guidelines on those issued by the American Society for Reproductive Medicine (ASRM). The recommended number of embryos, to be transferred, is mainly determined by the age of the patient, the stage at which embryos are transferred (day 3 or 5), as well as by factors associated with a "more or less favorable prognosis."

The standard transfer policy of Reproductive Medicine & Infertility Associates ("RMIA") is shown by age group.

Patient Age
Number of Embryos Transferred
< 35
Day 3: 2 (3 if less favorable* AND patient agreeable
Day 5: 2 (1 if more favorable**)
35-37
Day 3: 3 (2 if more favorable***)
Day 5: 2
38-40
Day 3: 3
Day 5: 3 (2 if more favorable**)
> 40
Day 3: 5
Day 5: 3

Recipients of donor oocytes
(All ages)
1, 2 or 3 based on the age of donor (see above guidelines)

*Less favorable prognosis, day 3:

a.Two or more previous failed fresh IVF cycles
OR
b. Poor embryo quality (No "good" embryo OR no ≥ 8 cell graded as "fair") on a second cycle.

**More favorable prognosis, day 5:

a.Previous successful cycle
OR
b.First/second cycle with high quality day 5 embryos (Hatching Blastocyst, grade 2 or better, OR Blastocyst grade 1).

***More favorable prognosis, day 3:

a.Previous successful cycle
OR
b.First/second cycle with two "good" embryos.


Guidelines dates 1/1/2010